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Administration: Oral use. The capsules should be taken with liquid.
Dosage: Acute diarrhoea: Adults and children over 12: 2 capsules (4 mg) initially followed by 1 capsule (2 mg) after every loose stool. The maximum daily dose should not exceed 6 capsules (12 mg).
Symptomatic treatment of acute episodes of diarrhoea associated with Irritable Bowel Syndrome (IBS) in adults aged 18 years and over: Two capsules (4 mg) to be taken initially, followed by 1 capsule (2 mg) after every loose stool, or as previously advised by the doctor. The maximum daily dose should not exceed 6 capsules (12 mg).
Paediatric population: Loperamide is contraindicated in children less than 12 years of age.
Elderly: No dose adjustment is required for the elderly.
Renal impairment: No dose adjustment is required for patients with renal impairment.
Hepatic impairment: Although no pharmacokinetic data are available in patients with hepatic impairment, loperamide should be used with caution in such patients because of reduced first pass metabolism.
